Purdue quarterback David Blough threw for 572 yards in a 40-37 loss to Missouri Saturday night. (Photos by Dave Deak)

WEST LAFAYETTE – Tucker McCann kicked a 25-yard field goal as time expired to lift Missouri to a 40-37 victory over the Boilermakers.

Missouri (3-0) is off to its best start since 2015 while Purdue (0-3) faces its worst beginning of the season since 1996 when they last opened with three losses. It was the second straight week Purdue has lost on a last-second field goal, losing 20-19 at home to Eastern Michigan last weekend.

Rondale Moore works upfield against Missouri.

The Tigers turned to McCann often to help stay ahead of the Boilermakers. He was 4 of 5 on field goals, including the game-winner.

Drew Lock finished 26-of-43 passing for 375 yards with three touchdowns and an interception for Missouri. He ran for negative-10 yards and a TD.

David Blough was 39-of-55 passing and had a career-high and program record 572 yards passing for the Boilermakers. He threw three touchdown passes and an interception, and ran for 18 yards on six carries with a touchdown.

“I do think we played to win,” Purdue coach Jeff Brohm said. “I think we played aggressive. Unfortunately, I don’t think we’re a good football team right now. I think anybody who watched us play knows that. We’ve got a lot of work to do to get better.”

The Boilermakers also relied on their kicker. Spencer Evans was 3 of 4 on field goals, including a 26-yarder with 3:28 remaining to tie the game at 37.

That came at the end of a thrilling and chaotic finish after the Boilermakers came back from 17 points down in the first half and tied the game twice. They tied it 27-27 with Evans’ 29-yard field goal early in the third quarter.

Missouri regained the lead when Larry Rountree III broke away for a 52-yard run and Lock scored on an 8-yard TD to make it 34-27. The Tigers scored again on McCann’s 31-yard field goal to make it 37-27 with 2:30 left in the third.

Purdue still had its opportunities. After scoring at the end of an odd two-play drive in the fourth, Blough threw a pass intended for running back Markell Jones, but the ball bounced off a defender and to Hopkins, who went 74 yards to set up Blough’s 7-yard TD pass to make it 37-34 with 12:16 remaining.

Lock was later picked off by Kenneth Major, leading to Evans tying the game late.